The Eyes Have It: Use of Pupillometry to Assess Cognition in Multiple Sclerosis

Can we detect small thinking impairments in adults with Multiple Sclerosis by measuring their pupil size?


The objective of this study is to determine if it is possible to use non-invasive neurophysiological measurements as potential markers of subtle cognitive impairments in individuals who are at risk for developing and worsening cognitive impairment in Multiple Sclerosis.


We will record your pupil dilation with non-invasive tools while you are engaging in different cognitive tests. This will take two hours. If eligible, you may be compensated $50 for your time.

Eligibility Criteria

You are eligible to participate if you meet the following:

1. Being cognitively intact, or having mild cognitive impairment

2. Aged 18 - 65 years old

3. Have no history of neurological conditions other than Multiple Sclerosis

4. Have no problems with your eyes or pupils, except for corrective glasses or contact lenses

Principal Investigator

Hannes Devos, PhD

Study Contact

Bunmi Morohunfola,, 913-945-9673

Estimated Completion Date

Wednesday, July 4, 2018