Active Studies

This study will evaluate the efficacy of VX-445 in triple combination (TC) with tezacaftor
(TEZ) and ivacaftor (IVA) in subjects with cystic fibrosis (CF) who are heterozygous for
F508del and a minimal function mutation (F/MF subjects).

This will be an open-label trial to describe the effects of cryoneurolysis with iovera° on
symptom relief in patients with painful Kellgren-Lawrence (KL) grade 2-4 ankle osteoarthritis
(OA). The Foot and Ankle Outcome Score (FAOS) subscales will be used to assess outcomes at 6,
12 and 24 weeks after treatment.

The University of Kansas
Medical Center is looking for women in the Kansas City area to
participate in a study highlighting the reproductive experiences of Black women dealing with infertility.

The purpose of this study is to evaluate whether axicabtagene ciloleucel therapy improves the
clinical outcome compared with standard of care second-line therapy in patients with
relapsed/refractory DLBCL.

The purpose of this study is to find a dose of hydralazine that would be best to treat patient with ADPKD

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