Active Studies

The purpose of this study is to assess the long-term safety of vedolizumab versus other
biologic agents in participants with Ulcerative Colitis (UC) or Crohn's Disease (CD).

Our team wants to better understand the impact of fatigue and inattention on commercial drivers' safety. Our goal is to help truck drivers drive longer and safer. We won't be sharing the results and we will help our participants with useful information that will assist them in any concerns we may find.

This is a multicenter, double-blind, randomized, placebo-controlled study to evaluate the
safety and efficacy of emricasan in improving event-free survival based on a composite
clinical endpoint (where all-cause mortality, new decompensation events, and MELD score
progression are events) in subjects with decompensated NASH cirrhosis.

This study will evaluate the efficacy of VX-445 in triple combination (TC) with tezacaftor
(TEZ) and ivacaftor (IVA) in subjects with cystic fibrosis (CF) who are heterozygous for
F508del and a minimal function mutation (F/MF subjects).

This will be an open-label trial to describe the effects of cryoneurolysis with iovera° on
symptom relief in patients with painful Kellgren-Lawrence (KL) grade 2-4 ankle osteoarthritis
(OA). The Foot and Ankle Outcome Score (FAOS) subscales will be used to assess outcomes at 6,
12 and 24 weeks after treatment.

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