This is a long-term study in cystic fibrosis patients who are participating in the Cystic
Fibrosis Patient Registry to assess the occurrence and risk factors for a rare bowel
disorder called fibrosing colonopathy (narrowing of the large intestine). Patients will be
followed at their regular clinical care visits over a 10-year period and approached if they
develop symptoms of fibrosing colonopathy for collection and use of further detailed
By doing this study, the researchers hope to develop new tools to explain why some normal-hearing listeners, who have been exposed to noise, have more difficulty understanding speech in background noise than their peers.
The purpose of the study is to develop a new method for understanding how the body breaks down certain medications by the metabolic enzyme, CYP2A6. Genetic variations are known to occur with this enzyme and this study will also evaluate the effect of genetic variation on the breakdown of medications through this pathway.
The proposed research is intended to determine if supplementation of relatively high dose
vitamin D in chronic urticaria patients receiving omalizumab will result in continued
symptomatic control of hives after the discontinuation of omalizumab.
The purpose of this study is to learn how much DHA to give to mothers in order to provide
enough to the baby. Researchers will also learn if there are differences in development of
the baby up to 12 months after birth.