The purpose of this study is to evaluate whether a blood pressure treatment strategy during pregnancy to achieve targets that are recommended for non-pregnant reproductive-age adults (

This study compares EG-1962 to enteral nimodipine in the treatment of aneurysmal
subarachnoid hemorrhage.

This is a long-term study in cystic fibrosis patients who are participating in the Cystic
Fibrosis Patient Registry to assess the occurrence and risk factors for a rare bowel
disorder called fibrosing colonopathy (narrowing of the large intestine). Patients will be
followed at their regular clinical care visits over a 10-year period and approached if they
develop symptoms of fibrosing colonopathy for collection and use of further detailed

The purpose of this research study is to help determine whether practicing resisting the
urge to smoke changes brain function or behavior among smokers.

By doing this study, the researchers hope to develop new tools to explain why some normal-hearing listeners, who have been exposed to noise, have more difficulty understanding speech in background noise than their peers.

The purpose of this study is to determine whether the researchers can help people change the
amount of time they spend in sitting activities and whether this change might improve health

The purpose of the study is to develop a new method for understanding how the body breaks down certain medications by the metabolic enzyme, CYP2A6.  Genetic variations are known to occur with this enzyme and this study will also evaluate the effect of genetic variation on the breakdown of medications through this pathway.

The proposed research is intended to determine if supplementation of relatively high dose
vitamin D in chronic urticaria patients receiving omalizumab will result in continued
symptomatic control of hives after the discontinuation of omalizumab.

The purpose of this study is to learn how much DHA to give to mothers in order to provide
enough to the baby. Researchers will also learn if there are differences in development of
the baby up to 12 months after birth.

The aim of this study is to compare outcomes and cost-effectiveness of anterior versus
posterior surgical treatment for lumbar Isthmic Spondylolisthesis. The primary objective is
to compare treatment effectiveness in terms of functional outcomes as measured by Oswestry
Disability Index (ODI) v2.1a and to compare safety outcomes measured by treatment-related
adverse events. Secondary objectives are to compare treatments in terms of differences in
pain, quality of life, health utilities, and need for re-operation. Finally, a
cost-effectiveness analysis will be performed. This analysis will take the form of
cost-effectiveness if there is a difference in treatment effects or cost-minimization if
there is no difference in treatment efficacy.