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Vitamin D for the Prevention of Migraine Headache in Adolescents

Study objective: Researchers are interested to find out if Vitamin D supplementation can help prevent migraine headaches in adolescents.

Am I eligible? Participants should be English-speaking adolescents aged 13-17 with a history of migraines and/or headaches occurring at least 1 time per week. You may not be able to participate in this study if you have a history or medical exam suggesting headaches that are secondary to another physical or developmental cause; if you have headaches less than 1 time each week; or if you have a history of mental illness or are under the care of psychiatrist. You may also be ineligible if you have a baseline Vitamin D level or more than 100 ng/ml or if you have a history of granulomatous disease (such as sarcoidosis, TB, Crohn's disease, etc.).

What is involved? This is a 12-week study which involves filling out pain diaries and questionnaires at the beginning and end
of the study; blood draws for Vitamin D levels at the beginning, middle, and end of the study; and taking Vitamin D or a placebo daily for 8 weeks. There is no charge for the blood work or for the medications. Participants will be paid $40.00 for full participation.

Keywords: headaches, migraines, vitamin D, adolescents


Principal Investigator

Joy Weydert, MD

Study Contact

Jean Sunega, jsunega@kumc.edu, 913-588-6104 or Dr. Joy Weydert, jweydert@kumc.edu, 913-588-6364